Endocrine Abstracts

Introduction: Giant prolactinomas are rare tumours, representing 2–3% of all prolactin (PRL)-secreting tumours. Their definition is restricted to pituitary adenomas with a diameter ≥4 or ≥2 cm of suprasellar extension, very high PRL concentrations (≥1000 ng/ml) and no concomitant GH or ACTH secretion. They are more common in young to middle-aged men. Endocrine symptoms are often present for a long period of time, but most times the diagnosis is made when...